Identification and functional characterization of a novel cationic amino acid transporter CAT5 specifically expressed in placenta
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چکیده
منابع مشابه
Identification and characterization of an amino acid transporter expressed differentially in liver.
Cellular metabolic needs are fulfilled by transport of amino acids across the plasma membrane by means of specialized transporter proteins. Although many of the classical amino acid transporters have been characterized functionally, less than half of these proteins have been cloned. In this report, we identify and characterize a cDNA encoding a plasma membrane amino acid transporter. The deduce...
متن کاملA putative amino acid transporter is specifically expressed in haustoria of the rust fungus Uromyces fabae.
A cDNA library constructed from haustoria of the rust fungus Uromyces fabae was screened for clones that are differentially expressed in haustoria. One family of cDNAs (in planta-induced gene 2 [PIG2] was isolated and found to encode a protein with high homologies to fungal amino acid transporters. A cDNA clone containing the complete coding region of PIG2 and the corresponding genomic clone we...
متن کاملPtAAP11, a high affinity amino acid transporter specifically expressed in differentiating xylem cells of poplar.
Amino acids are the currency of nitrogen exchange between source and sink tissues in plants and constitute a major source of the components used for cellular growth and differentiation. The characterization of a new amino acid transporter belonging to the amino acid permease (AAP) family, AAP11, expressed in the perennial species Populus trichocarpa is reported here. PtAAP11 expression analysis...
متن کاملSNAT4 isoform of system A amino acid transporter is expressed in human placenta.
The system A amino acid transporter is encoded by three members of the Slc38 gene family, giving rise to three subtypes: Na+-coupled neutral amino acid transporter (SNAT)1, SNAT2, and SNAT4. SNAT2 is expressed ubiquitously in mammalian tissues; SNAT1 is predominantly expressed in heart, brain, and placenta; and SNAT4 is reported to be expressed solely by the liver. In the placenta, system A has...
متن کاملThe SNAT4 isoform of the system A amino acid transporter is expressed in human placenta
The system A amino acid transporter is encoded by three members of the Slc38 gene family giving rise to three subtypes: SNAT1, SNAT2, and SNAT4. SNAT2 is expressed ubiquitously in mammalian tissues, SNAT1 is predominantly expressed in heart, brain, and placenta while SNAT4 is reported to be expressed uniquely by the liver. In the placenta, system A has an essential role in the supply of neutral...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.5.a840-b